SCHEMBL14966890

SCHEMBL14966890

CCCCCCOC(=O)C12CCCCC1(CC)O2

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.40
EPHX1 P07099 1/20 0.38
TSHR P16473 2/20 0.37
PRKCA P17252 7/20 0.36
CES2 O00748 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
RAD52 P43351 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PSEN1 P49768 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967912 0.99 NAAA (0.39) NAAAEPHX1TSHRPRKCACES2
SCHEMBL14968051 0.99 NAAA (0.38) NAAAEPHX1TSHRPRKCACES2
SCHEMBL14967758 0.97 NAAA (0.37) NAAAEPHX1TSHRPRKCAHCAR2
SCHEMBL14967889 0.97 NAAA (0.40) NAAAEPHX1TSHRPRKCACES2
SCHEMBL14967643 0.96 NAAA (0.38) NAAAEPHX1TSHRPRKCACES2
SCHEMBL14967485 0.94 ALDH1A1 (0.38) NAAAEPHX1TSHRHCAR2NPSR1
SCHEMBL14967124 0.93 ALDH1A1 (0.37) NAAATSHRHCAR2NPSR1
SCHEMBL14967682 0.91 ALDH1A1 (0.38) NAAAEPHX1TSHRHCAR2PSEN1
SCHEMBL14968148 0.88 CYP3A4 (0.32) TSHRNPSR1
SCHEMBL14966672 0.87 CYP3A4 (0.34) TSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed