SCHEMBL14967758

SCHEMBL14967758

CCCCCOC(=O)C12CCCCCC1(CC)O2

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.37
EPHX1 P07099 1/20 0.35
MAPK1 P28482 2/20 0.35
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TSHR P16473 3/20 0.34
PRKCA P17252 7/20 0.33
PSEN1 P49768 3/20 0.33
HCAR2 Q8TDS4 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967912 0.99 NAAA (0.39) NAAAEPHX1NPSR1TSHRPRKCA
SCHEMBL14968051 0.99 NAAA (0.38) NAAAEPHX1TSHRPRKCAPSEN1
SCHEMBL14966890 0.97 NAAA (0.40) NAAAEPHX1NPSR1TSHRPRKCA
SCHEMBL14967643 0.96 NAAA (0.38) NAAAEPHX1TSHRPRKCAPSEN1
SCHEMBL14967124 0.96 ALDH1A1 (0.37) NAAAMAPK1MAPTNPSR1L3MBTL1
SCHEMBL14967889 0.94 NAAA (0.40) NAAAEPHX1NPSR1TSHRPRKCA
SCHEMBL14967485 0.94 ALDH1A1 (0.38) NAAAEPHX1MAPK1NPSR1L3MBTL1
SCHEMBL14967682 0.91 ALDH1A1 (0.38) NAAAEPHX1MAPK1L3MBTL1TSHR
SCHEMBL14966672 0.90 CYP3A4 (0.34) MAPK1NPSR1TSHRCYP3A4
SCHEMBL14968148 0.88 CYP3A4 (0.32) MAPK1NPSR1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed