SCHEMBL14966947

SCHEMBL14966947

CCCOC(=O)C1(CC)OC1c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.39
TSHR P16473 1/20 0.39
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
GAA P10253 1/20 0.38
PPARG P37231 3/20 0.36
MAOB P27338 2/20 0.36
NPC1 O15118 1/20 0.36
TP53 P04637 1/20 0.36
RAB9A P51151 1/20 0.36
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967026 0.91 PPARG (0.48) LMNAALDH1A1KDM4ETSHRMAPT
SCHEMBL14967649 0.89 PPARG (0.50) LMNAALDH1A1KDM4ETSHRMAPT
SCHEMBL14967143 0.88 TSHR (0.48) ALDH1A1KDM4ETSHRKMT2ASMN1; SMN2
SCHEMBL14966700 0.87 ALDH1A1 (0.34) LMNAALDH1A1KDM4ETSHRMAPT
SCHEMBL14967171 0.85 ALDH1A1 (0.41) LMNAALDH1A1KDM4ETSHRKMT2A
SCHEMBL14967651 0.84 LMNA (0.45) LMNAALDH1A1KDM4ETSHRMAPT
SCHEMBL14968287 0.84 MAPT (0.41) LMNAALDH1A1TSHRMAPTKMT2A
SCHEMBL14967763 0.82 KMT2A (0.38) LMNAALDH1A1KDM4ETSHRMAPT
SCHEMBL14967898 0.81 MAPT (0.39) ALDH1A1KDM4ETSHRMAPTKMT2A
SCHEMBL14968339 0.80 TSHR (0.40) LMNAALDH1A1KDM4ETSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed