SCHEMBL14968339

SCHEMBL14968339

CCC1(C(=O)OC(C)C)OC1c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
PYGM P11217 2/20 0.38
PYGL P06737 1/20 0.38
KMT2A Q03164 3/20 0.36
MAPT P10636 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
ALDH1A1 P00352 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
LMNA P02545 2/20 0.34
ALOX12 P18054 1/20 0.34
MEN1 O00255 1/20 0.34
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967023 0.87 ABHD10 (0.41) PYGMPYGLKMT2AMAPTALDH1A1
SCHEMBL16109030 0.85 NPC1 (0.40) TSHRKMT2AMAPTNPSR1ALDH1A1
SCHEMBL14968287 0.84 MAPT (0.41) TSHRKMT2AMAPTNPSR1ALDH1A1
SCHEMBL14967143 0.82 TSHR (0.48) TSHRKMT2AALDH1A1SMN1; SMN2MEN1
SCHEMBL14967898 0.81 MAPT (0.39) TSHRKMT2AMAPTNPSR1ALDH1A1
SCHEMBL14967706 0.81 TSHR (0.39) TSHRPYGMPYGLKMT2AMAPT
SCHEMBL14966947 0.80 LMNA (0.44) TSHRKMT2AMAPTNPSR1ALDH1A1
SCHEMBL273608 0.80 TSHR (0.39) TSHRKMT2AMAPTNPSR1ALDH1A1
SCHEMBL8876521 0.80 TSHR (0.39) TSHRKMT2AMAPTNPSR1ALDH1A1
SCHEMBL4884144 0.80 TSHR (0.39) TSHRKMT2AMAPTNPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed