SCHEMBL14966966

SCHEMBL14966966

CCC1(CC)OC1(C(=O)Oc1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
POLB P06746 1/20 0.43
ELANE P08246 1/20 0.36
MAPT P10636 2/20 0.36
HCAR3 P49019 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
ZDHHC2 Q9UIJ5 1/20 0.36
OPRM1 P35372 5/20 0.35
TDP1 Q9NUW8 2/20 0.35
KDM4E B2RXH2 1/20 0.35
OPRD1 P41143 3/20 0.35
OPRK1 P41145 3/20 0.35
SLC22A1 O15245 1/20 0.35
SLC6A4 P31645 1/20 0.35
ADRA1A P35348 1/20 0.35
KCNH2 Q12809 1/20 0.35
ATM Q13315 1/20 0.34
RAB9A P51151 1/20 0.34
MEN1 O00255 1/20 0.34
MITF O75030 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14968226 0.89 ZDHHC2 (0.40) L3MBTL1POLBZDHHC2
SCHEMBL9692257 0.84 MEN1 (0.45) MAPTHCAR3HCAR2OPRM1KDM4E
SCHEMBL14968155 0.80 LMNA (0.46) POLBOPRM1TDP1KDM4EOPRD1
SCHEMBL14967731 0.79 L3MBTL1 (0.42) L3MBTL1POLBELANEMAPTTDP1
SCHEMBL14968127 0.78 L3MBTL1 (0.41) L3MBTL1POLBELANEMAPTTDP1
SCHEMBL14968235 0.74 POLB (0.42) L3MBTL1POLBMAPTTDP1KDM4E
SCHEMBL14967038 0.74 POLB (0.42) L3MBTL1POLBKDM4E
SCHEMBL14967132 0.74 HTT (0.41) L3MBTL1ELANEOPRM1TDP1MEN1
SCHEMBL16109920 0.74 GAA (0.42) L3MBTL1POLBMAPTOPRM1TDP1
SCHEMBL14968048 0.73 POLB (0.41) L3MBTL1POLBELANEMAPTZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed