SCHEMBL14967731

SCHEMBL14967731

O=C(Oc1ccccc1)C1(c2ccccc2)OC1(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.42
POLB P06746 1/20 0.42
TDP1 Q9NUW8 2/20 0.38
MAPT P10636 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ATM Q13315 2/20 0.37
HSD17B10 Q99714 2/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
FAAH O00519 1/20 0.35
NSD2 O96028 1/20 0.34
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP19A1 P11511 1/20 0.33
ELANE P08246 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16109920 0.90 GAA (0.42) L3MBTL1POLBTDP1MAPTFAAH
SCHEMBL14967348 0.89 POLB (0.41) L3MBTL1POLBMAPTALDH1A1KMT2A
SCHEMBL14966918 0.88 ALDH1A1 (0.43) L3MBTL1POLBTDP1MAPTFAAH
SCHEMBL14966942 0.81 KMT2A (0.47) POLBMAPTKDM4EHSD17B10HPGD
SCHEMBL14966966 0.79 L3MBTL1 (0.43) L3MBTL1POLBTDP1MAPTKDM4E
SCHEMBL14967038 0.78 POLB (0.42) L3MBTL1POLBKDM4EFAAH
SCHEMBL14968235 0.78 POLB (0.42) L3MBTL1POLBTDP1MAPTKDM4E
SCHEMBL14967521 0.77 TSHR (0.40) MAPTATMALDH1A1MEN1KMT2A
SCHEMBL14968306 0.77 TSHR (0.34) TDP1ATMHSD17B10ALOX15ALDH1A1
SCHEMBL14968062 0.77 OPRM1 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed