SCHEMBL14967654

SCHEMBL14967654

CCC1(c2ccc(OC)cc2)OC1C(=O)OC1CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
SLC6A2 P23975 1/20 0.38
RAB9A P51151 2/20 0.38
ALDH1A1 P00352 5/20 0.38
TSHR P16473 2/20 0.38
HSD11B1 P28845 1/20 0.37
GAA P10253 3/20 0.36
HTT P42858 1/20 0.36
EPHX2 P34913 1/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16109861 0.95 EPHX2 (0.39) ATML3MBTL1MEN1KMT2ASLC6A4
SCHEMBL16109610 0.95 SLC6A4 (0.40) ATML3MBTL1MEN1KMT2ASLC6A4
SCHEMBL16110551 0.94 EPHX2 (0.41) ATML3MBTL1MEN1KMT2ASLC6A4
SCHEMBL16109685 0.87 SCN1A (0.36) MEN1KMT2ASLC6A4SLC6A3SLC6A2
SCHEMBL14967321 0.85 FABP7 (0.38) L3MBTL1MEN1KMT2AALDH1A1TSHR
SCHEMBL14967027 0.85 ALDH1A1 (0.45) MEN1KMT2ARAB9AALDH1A1TSHR
SCHEMBL14967768 0.85 ATM (0.44) ATML3MBTL1RAB9AALDH1A1HSD11B1
SCHEMBL16110262 0.82 CHRNA1 (0.37) L3MBTL1MEN1KMT2ASLC6A4SLC6A3
SCHEMBL16108665 0.82 CHRNA1 (0.39) L3MBTL1SLC6A4SLC6A3SLC6A2HSD11B1
SCHEMBL14967372 0.81 MEN1 (0.44) ATML3MBTL1MEN1KMT2ASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed