SCHEMBL9692301

SCHEMBL9692301

CCC1(c2ccccc2)OC1C(=O)OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.45
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
ITGA4 P13612 1/20 0.41
HCAR3 P49019 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39
POLB P06746 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
CYP3A4 P08684 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ALOX15 P16050 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP2C9 P11712 2/20 0.36
MAPK1 P28482 1/20 0.36
CYP2D6 P10635 1/20 0.36
TSHR P16473 1/20 0.36
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967939 0.86 TSHR (0.48) HTTALDH1A1HCAR3HCAR2MEN1
SCHEMBL9692237 0.86 TDP1 (0.36) ALDH1A1MAPTITGA4KMT2AMMP2
SCHEMBL9691924 0.86 HTT (0.44) HTTALDH1A1MAPTITGA4POLB
SCHEMBL14967768 0.85 ATM (0.44) HTTALDH1A1POLBATM
SCHEMBL9691702 0.85 ALDH1A1 (0.36) ALDH1A1MAPTITGA4HCAR3HCAR2
SCHEMBL14967432 0.85 ELANE (0.38) HTTALDH1A1MAPTHCAR3HCAR2
SCHEMBL14967754 0.84 LMNA (0.44) ALDH1A1HCAR3HCAR2TSHR
SCHEMBL14967326 0.84 ABCB1 (0.37) HTTHCAR3HCAR2MEN1KMT2A
SCHEMBL14967403 0.84 TSHR (0.40) HTTMAPTHCAR3HCAR2TSHR
SCHEMBL9692732 0.84 MAPT (0.41) HTTALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed
EP-0153692-B1 METHOD FOR ISOMERIZATION A GLYCIDATE DERIVATIVE SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-07-29 EP disclosed
US-4621150-A METAL PERHALATE OR SULFONATE OR COMPLEX; GLYCIDATE, 2-HYDROXY-3-BUTENOATE, EPOXIDE SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-11-04 US disclosed
EP-0153692-A2 Method for isomerization a glycidate derivative SAGAMI CHEMICAL RESEARCH CENTER (JP) 1985-09-04 EP disclosed