Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11303021 | 0.92 | LMNA (0.65) | LMNACYP1A2AGTR1SMN1; SMN2KDM4E | |
| SCHEMBL29941729 | 0.86 | LMNA (0.82) | LMNACYP1A2AGTR1SMN1; SMN2KDM4E | |
| SCHEMBL2328960 | 0.86 | LMNA (0.82) | LMNACYP1A2AGTR1SMN1; SMN2KDM4E | |
| SCHEMBL27251161 | 0.84 | ALOX15 (0.62) | LMNACYP1A2AGTR1KDM4EL3MBTL1 | |
| SCHEMBL1446334 | 0.83 | LMNA (0.61) | LMNACYP1A2AGTR1SMN1; SMN2KDM4E | |
| SCHEMBL15658611 | 0.83 | LMNA (0.49) | LMNACYP1A2AGTR1SMN1; SMN2KDM4E | |
| SCHEMBL3308807 | 0.82 | LMNA (0.66) | LMNACYP1A2AGTR1SMN1; SMN2KDM4E | |
| SCHEMBL10263938 | 0.82 | LMNA (0.55) | LMNACYP1A2AGTR1KDM4EPOLB | |
| SCHEMBL10636086 | 0.82 | LMNA (0.47) | LMNACYP1A2AGTR1SMN1; SMN2KDM4E | |
| Guaifenesin SCHEMBL31161209 | 0.81 | CYP1A2 (1.00) | LMNACYP1A2AGTR1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114848640-B | Application of compound in preparation of anti-inflammatory drugs | 山东第一医科大学(山东省医学科学院) | 2023-04-07 | — | — | CN | claimed |
| CN-114848640-A | Application of compound in preparation of anti-inflammatory drugs | 山东第一医科大学(山东省医学科学院) | 2022-08-05 | — | — | CN | claimed |
| CN-119998412-A | Ink composition, layer using the same, and electrophoretic device and display device including the layer | 三星显示有限公司 | 2025-05-13 | — | — | CN | disclosed |
| WO-2024182479-A2 | COMPOUNDS AND METHODS OF TREATING OR PREVENTING A BACTERIAL INFECTION IN A PLANT | OHIO STATE INNOVATION FOUNDATION (US) | 2024-09-06 | — | — | WO | disclosed |
| US-20240093042-A1 | INK COMPOSITION, LAYER USING THE SAME, ELECTROPHORESIS DEVICE AND DISPLAY DEVICE COMPRISING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2024-03-21 | — | — | US | disclosed |
| CN-115385847-B | Polysubstituted diaryl compound, preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2023-09-29 | — | — | CN | disclosed |
| CN-114848640-B | Application of compound in preparation of anti-inflammatory drugs | 山东第一医科大学(山东省医学科学院) | 2023-04-07 | — | — | CN | disclosed |
| CN-115385847-A | Polysubstituted diaryl compound and preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2022-11-25 | — | — | CN | disclosed |
| CN-113387873-B | Substituted diaryl compound, preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2022-09-20 | — | — | CN | disclosed |
| CN-114848640-A | Application of compound in preparation of anti-inflammatory drugs | 山东第一医科大学(山东省医学科学院) | 2022-08-05 | — | — | CN | disclosed |
| US-7906667-B2 | Method for producing optically active alcohol compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-03-15 | — | — | US | disclosed |
| EP-1178973-B1 | PYRAZINYL-PIPERAZINE- COMPOUNDS, THEIR USE AND PREPARATION | BIOVITRUM AB (SE) | 2005-12-21 | — | — | EP | disclosed |
| US-20040242554-A1 | CERTAIN ARYLALIPHATIC AND HETEROARYL-ALIPHATIC PIPERAZINYL PYRAZINES AND THEIR USE IN THE TREATMENT OF SEROTONIN-RELATED DISEASES | BIOVITRUM, AB, A STOCKHOLM, SWEDEN CORPORATION | 2004-12-02 | — | — | US | disclosed |
| US-20030092694-A1 | Certain arylaliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases | BIOVITRUM, AB, A STOCKHOLM, SWEDEN CORPORATION | 2003-05-15 | — | — | US | disclosed |
| US-6465467-B1 | DISEASES RELATED TO THE 5-HT2C RECEPTOR, ESPECIALLY EATING, MEMORY, MOOD, URINARY AND ANXIETY DISORDERS, SCHIZOPHRENIA, PAIN, SEXUAL DYSFUNCTIONS | BIOVITRUM AB (SE) | 2002-10-15 | — | — | US | disclosed |
| EP-1178973-A2 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Pharmacia AB (SE) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000076984-A2 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | BIOVITRUM AB (SE) | 2000-12-21 | — | — | WO | disclosed |
| EP-0143381-B1 | BIPHENYLYLALKANOIC ACID DERIVATIVES, METHODS OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREFROM | Dr. L. ZAMBELETTI S.p.A. (IT) | 1988-03-09 | — | — | EP | disclosed |
| US-4570013-A | ANTIPYRETIC, ANALGESIC, ANTIINFLAMMATORY AGENTS; METHOXYPHENOXYPROPANOL ESTERS | DR. L. ZAMBELETTI S.P.A. (IT) | 1986-02-11 | — | — | US | disclosed |
| EP-0143381-A2 | Biphenylylalkanoic acid derivatives, methods of preparation and pharmaceutical compositions therefrom | Dr. L. ZAMBELETTI S.p.A. (IT) | 1985-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092694-A1 | Certain arylaliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases | HTR2C, HTR3C, HTR2A | LMNA 2553/4885CYP1A2 159/4885AGTR1 284/4885 |
| US-20040242554-A1 | CERTAIN ARYLALIPHATIC AND HETEROARYL-ALIPHATIC PIPERAZINYL PYRAZINES AND THEIR USE IN THE TREATMENT OF SEROTONIN-RELATED DISEASES | HTR2C, HTR3C, HTR2A | LMNA 2654/4885CYP1A2 157/4885AGTR1 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.