Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11295045 | 0.79 | LMNA (0.39) | NPSR1MAPTLMNAKMT2AMAOB | |
| SCHEMBL11205079 | 0.78 | NPSR1 (0.41) | NPSR1MAPTTSHRGAALMNA | |
| SCHEMBL11138063 | 0.73 | NPSR1 (0.38) | NPSR1MAPTGAALMNAKMT2A | |
| SCHEMBL14967385 | 0.71 | TSHR (0.39) | TSHRLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11269019 | 0.70 | ABCB11 (0.48) | MAPTTSHRGAALMNAKMT2A | |
| SCHEMBL11272688 | 0.69 | ABCB11 (0.52) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL10369206 | 0.68 | TSHR (0.68) | NPSR1MAPTTSHRGAALMNA | |
| SCHEMBL10062555 | 0.68 | ALDH1A1 (0.47) | MAPTTSHRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11296928 | 0.68 | ABCB11 (0.43) | MAPTTSHRGAALMNAKMT2A | |
| SCHEMBL1784913 | 0.68 | TSHR (0.37) | NPSR1MAPTTSHRGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |