Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.37 |
| ▸ | ACACB | O00763 | 6/20 | 0.37 |
| ▸ | MELK | Q14680 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14968064 | 0.90 | ALDH1A1 (0.40) | GRIN2BDGAT1KCNH2ADORA2ASOAT1 | |
| SCHEMBL14971854 | 0.85 | ERN1 (0.38) | GRIN2BDGAT1KCNH2ADORA2AACACB | |
| SCHEMBL14967450 | 0.82 | ERN1 (0.35) | GRIN2BFFAR4ACACBMELKERN1 | |
| SCHEMBL14969248 | 0.81 | CYP11B1 (0.38) | GRIN2BDGAT1KCNH2ADORA2AFFAR4 | |
| SCHEMBL14969247 | 0.81 | CYP11B1 (0.38) | GRIN2BDGAT1KCNH2ADORA2AFFAR4 | |
| SCHEMBL14969513 | 0.80 | ALDH1A1 (0.40) | GRIN2BDGAT1FFAR4MELKERN1 | |
| SCHEMBL14969514 | 0.80 | ALDH1A1 (0.40) | GRIN2BDGAT1FFAR4MELKERN1 | |
| SCHEMBL14968128 | 0.80 | MAPT (0.36) | GRIN2BFFAR4ERN1 | |
| SCHEMBL14971569 | 0.79 | DGAT1 (0.51) | GRIN2BDGAT1KCNH2ADORA2ASOAT1 | |
| SCHEMBL15055224 | 0.79 | DGAT1 (0.51) | GRIN2BDGAT1KCNH2ADORA2ASOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074387-A1 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2013-05-23 | — | — | WO | disclosed |