SCHEMBL14967620

SCHEMBL14967620

CCCCCOC(=O)C1OC1(C)C

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.46
EPHX1 P07099 1/20 0.43
TSHR P16473 4/20 0.42
ALDH1A1 P00352 2/20 0.41
HCAR2 Q8TDS4 2/20 0.41
PPARG P37231 3/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.40
RAD52 P43351 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
FAAH O00519 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967677 0.98 NAAA (0.48) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL14967555 0.94 ALDH1A1 (0.47) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL14967349 0.86 PPM1B (0.42) TSHRALDH1A1HCAR2LMNA
SCHEMBL14967084 0.84 NAAA (0.42) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL14967185 0.83 NAAA (0.44) NAAAEPHX1TSHRHCAR2PPARG
SCHEMBL14967327 0.82 NAAA (0.43) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL14967972 0.81 NAAA (0.46) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL31502874 0.79 NAAA (0.47) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL14967933 0.79 ALDH1A1 (0.42) NAAAEPHX1TSHRALDH1A1HCAR2
SCHEMBL16109629 0.78 NAAA (0.40) NAAAEPHX1TSHRHCAR2PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed