SCHEMBL14967933

SCHEMBL14967933

CCCCOC(=O)C1OC1(C)CC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
ATM Q13315 1/20 0.40
LMNA P02545 2/20 0.38
POLB P06746 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TSHR P16473 3/20 0.38
HPGD P15428 1/20 0.38
HCAR2 Q8TDS4 1/20 0.36
NAAA Q02083 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
PPM1B O75688 1/20 0.34
PTPN1 P18031 1/20 0.34
PPP1CC P36873 1/20 0.34
PPP5C P53041 1/20 0.34
MAPK1 P28482 2/20 0.33
PRKCA P17252 1/20 0.33
KDM4E B2RXH2 1/20 0.33
EPHX1 P07099 1/20 0.33
ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967084 0.95 NAAA (0.42) ALDH1A1TSHRHCAR2NAAAMAPK1
SCHEMBL14967185 0.93 NAAA (0.44) TSHRHCAR2NAAAPRKCAEPHX1
SCHEMBL14967693 0.89 PPM1B (0.42) ALDH1A1LMNATSHRHCAR2TDP1
SCHEMBL14967555 0.84 ALDH1A1 (0.47) ALDH1A1ATMLMNAPOLBSMN1; SMN2
SCHEMBL2139493 0.82 LMNA (0.40) ALDH1A1LMNAPOLBTSHRHPGD
SCHEMBL14967114 0.81 ALDH1A1 (0.44) ALDH1A1ATMLMNAPOLBSMN1; SMN2
SCHEMBL14967620 0.79 NAAA (0.46) ALDH1A1LMNATSHRHCAR2NAAA
SCHEMBL14967677 0.77 NAAA (0.48) ALDH1A1LMNATSHRHCAR2NAAA
SCHEMBL14967755 0.77 ALDH1A1 (0.40) ALDH1A1ATMLMNAPOLBSMN1; SMN2
SCHEMBL16109828 0.77 ALDH1A1 (0.40) ALDH1A1ATMLMNAPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed