Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5862676 | 0.84 | NLRP3 (0.52) | MAPTPOLBKMT2ANLRP3SMN1; SMN2 | |
| SCHEMBL11190983 | 0.84 | SMN1; SMN2 (0.62) | MAPTKMT2ANLRP3NPC1SMN1; SMN2 | |
| SCHEMBL9863061 | 0.83 | KMT2A (0.54) | KMT2ANLRP3SMN1; SMN2GAAPKM | |
| SCHEMBL4826133 | 0.82 | ALDH1A1 (0.62) | MAPTPOLBKMT2ANLRP3NPC1 | |
| SCHEMBL25474868 | 0.82 | MEN1 (0.57) | MAPTPOLBKMT2ASMN1; SMN2PKM | |
| SCHEMBL8231868 | 0.82 | ALDH1A1 (0.54) | MAPTPOLBKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14645571 | 0.81 | MEN1 (0.59) | MAPTPOLBKMT2ANLRP3NPC1 | |
| SCHEMBL30601894 | 0.81 | MEN1 (0.59) | MAPTPOLBKMT2ANLRP3NPC1 | |
| SCHEMBL2010247 | 0.81 | SMN1; SMN2 (0.69) | MAPTPOLBKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL7000095 | 0.80 | KDM4E (0.67) | MAPTPOLBKMT2ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2024-01-25 | — | — | US | disclosed |
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230270111-A1 | PYRROLIDINONES HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY | 2023-08-31 | — | — | US | disclosed |
| US-11589583-B2 | Pyrrolidinones herbicides | FMC CORPORATION (US) | 2023-02-28 | — | — | US | disclosed |
| US-11528906-B2 | Pyrrolidinones as herbicides | FMC CORPORATION (US) | 2022-12-20 | — | — | US | disclosed |
| EP-3663282-B1 | PYRROLIDINONE HERBICIDES | FMC CORP (US) | 2022-05-18 | — | — | EP | disclosed |
| US-20220132844-A1 | PYRROLIDINONES AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY | 2022-05-05 | — | — | US | disclosed |
| US-20220127229-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2022-04-28 | — | — | US | disclosed |
| US-20220030863-A9 | PYRROLIDINONES HERBICIDES | FMC CORPORATION | 2022-02-03 | — | — | US | disclosed |
| US-11180453-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2021-11-23 | — | — | US | disclosed |
| US-9328138-B2 | HCV NS3 protease inhibitors | MSD ITALIA S.R.L. (IT) | 2016-05-03 | — | — | US | disclosed |
| US-9328138-B2 | HCV NS3 protease inhibitors | MSD ITALIA S.R.L. (IT) | 2016-05-03 | — | — | US | disclosed |
| US-9328138-B2 | HCV NS3 protease inhibitors | MSD ITALIA S.R.L. (IT) | 2016-05-03 | — | — | US | disclosed |
| WO-2015084796-A1 | PYRROLIDINONES AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-06-11 | — | — | WO | disclosed |
| US-20140296136-A1 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME LLC | 2014-10-02 | — | — | US | disclosed |
| US-20140296136-A1 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME LLC | 2014-10-02 | — | — | US | disclosed |
| US-20140296136-A1 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME LLC | 2014-10-02 | — | — | US | disclosed |
| EP-2780026-A2 | HCV NS3 PROTEASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013074386-A2 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013074386-A2 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11589583-B2 | Pyrrolidinones herbicides | DDT, ARG1, CYP1B1 | MAPT 3973/4885POLB 2085/4885KMT2A 2246/4885 |
| US-20220132844-A1 | PYRROLIDINONES AS HERBICIDES | DDT, ARG1, PRMT1 | MAPT 4172/4885POLB 2382/4885KMT2A 1619/4885 |
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | MAPT 3629/4885POLB 3194/4885KMT2A 1699/4885 |
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | MAPT 3633/4885POLB 3164/4885KMT2A 1693/4885 |
| US-20230270111-A1 | PYRROLIDINONES HERBICIDES | DDT, ARG1, CYP1B1 | MAPT 3973/4885POLB 2085/4885KMT2A 2246/4885 |
| US-11528906-B2 | Pyrrolidinones as herbicides | DDT, ARG1, PRMT1 | MAPT 4172/4885POLB 2382/4885KMT2A 1619/4885 |
| US-20220127229-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | MAPT 3629/4885POLB 3194/4885KMT2A 1699/4885 |
| US-20140296136-A1 | HCV NS3 PROTEASE INHIBITORS | HAVCR2, GTF3C3, CTSC | MAPT 4330/4885POLB 2914/4885KMT2A 3629/4885 |
| US-20220030863-A9 | PYRROLIDINONES HERBICIDES | DDT, ARG1, CYP1B1 | MAPT 3973/4885POLB 2085/4885KMT2A 2246/4885 |
| US-11180453-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | MAPT 3629/4885POLB 3194/4885KMT2A 1699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.