SCHEMBL14967704

SCHEMBL14967704

Cc1ccc(C2(c3ccc(C)cc3)OC2C(=O)Oc2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.40
LMNA P02545 1/20 0.39
ALDH1A1 P00352 4/20 0.38
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
PPARG P37231 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MAPT P10636 1/20 0.37
GAA P10253 1/20 0.36
PTGES O14684 1/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16110559 0.99 USP2 (0.39) USP2LMNAALDH1A1KMT2AMEN1
SCHEMBL16109149 0.93 GAA (0.42) LMNAALDH1A1KMT2ASMN1; SMN2MAPT
SCHEMBL14968010 0.89 ALDH1A1 (0.42) ALDH1A1MAPTGAACRHBPCRHR2
SCHEMBL14968072 0.87 HTT (0.43) ALDH1A1KMT2ASMN1; SMN2MAPTGAA
SCHEMBL16109558 0.86 HTT (0.42) ALDH1A1KMT2ASMN1; SMN2MAPTGAA
SCHEMBL16109556 0.85 USP2 (0.40) USP2LMNAALDH1A1KMT2AMEN1
SCHEMBL16109853 0.84 HTT (0.44) LMNAALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL16108688 0.81 USP2 (0.36) USP2LMNAALDH1A1KMT2AMEN1
SCHEMBL16108982 0.80 OPRM1 (0.35) LMNAKMT2AMEN1SMN1; SMN2CRHBP
SCHEMBL16110030 0.80 ALDH1A1 (0.36) LMNAALDH1A1KMT2AMEN1CRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140319472-A1 ORGANIC LIGHT-EMITTING DIODE SAMSUNG DISPLAY CO., LTD. (KR) 2014-10-30 US disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed