SCHEMBL14968010

SCHEMBL14968010

O=C(Oc1ccccc1)C1OC1(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
ELANE P08246 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
GAA P10253 2/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HTT P42858 2/20 0.36
POLB P06746 1/20 0.36
FABP7 O15540 1/20 0.36
FABP3 P05413 1/20 0.36
FABP5 Q01469 1/20 0.36
P4HB P07237 1/20 0.36
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16110559 0.91 USP2 (0.39) ALDH1A1CRHBPCRHR2MAPTGAA
SCHEMBL16109558 0.90 HTT (0.42) ALDH1A1TDP1MAPTGAAL3MBTL1
SCHEMBL14967704 0.89 USP2 (0.40) ALDH1A1CRHBPCRHR2MAPTGAA
SCHEMBL14968072 0.88 HTT (0.43) ALDH1A1TDP1MAPTGAAL3MBTL1
SCHEMBL16109149 0.83 GAA (0.42) ALDH1A1MAPTGAAHTTRAB9A
SCHEMBL16109691 0.81 ALDH1A1 (0.41) ALDH1A1ELANETDP1KDM4EMAPT
SCHEMBL570250 0.81 HTT (0.50) ALDH1A1CRHBPCRHR2MAPTGAA
SCHEMBL14968285 0.79 ALDH1A1 (0.45) ALDH1A1ELANETDP1KDM4EMAPT
SCHEMBL6729826 0.77 CRHBP (0.61) ALDH1A1CRHBPCRHR2HTTPOLB
SCHEMBL8993551 0.77 CRHBP (0.61) ALDH1A1CRHBPCRHR2HTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed