SCHEMBL14967804

SCHEMBL14967804

Cc1ccc(C2(C(=O)Oc3ccccc3)OC23CCCC3)cc1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
FAAH O00519 7/20 0.38
TRPV1 Q8NER1 4/20 0.38
KDM4E B2RXH2 2/20 0.37
LMNA P02545 2/20 0.37
USP2 O75604 1/20 0.36
HPGD P15428 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967781 0.99 FAAH (0.40) POLBL3MBTL1FAAHTRPV1KDM4E
SCHEMBL14967569 0.97 POLB (0.40) POLBL3MBTL1FAAHTRPV1KDM4E
SCHEMBL14967038 0.90 POLB (0.42) POLBL3MBTL1FAAHTRPV1KDM4E
SCHEMBL14967115 0.89 FAAH (0.43) POLBL3MBTL1FAAHTRPV1KDM4E
SCHEMBL14967817 0.88 FAAH (0.50) POLBL3MBTL1FAAHTRPV1KDM4E
SCHEMBL14968235 0.88 POLB (0.42) POLBL3MBTL1FAAHTRPV1KDM4E
SCHEMBL14969500 0.87 FAAH (0.52) POLBL3MBTL1FAAHTRPV1KDM4E
SCHEMBL14968020 0.86 FAAH (0.47) POLBL3MBTL1FAAHTRPV1KDM4E
SCHEMBL14968327 0.82 CYP3A4 (0.42) POLBKDM4ELMNAHPGDALDH1A1
SCHEMBL14967348 0.81 POLB (0.41) POLBL3MBTL1LMNAUSP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed