SCHEMBL14967115

SCHEMBL14967115

O=C(Oc1ccccc1)C1(c2ccccc2)OC12CCCCC2

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.43
TRPV1 Q8NER1 6/20 0.41
POLB P06746 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KDM4E B2RXH2 1/20 0.40
AKR1C1 Q04828 1/20 0.40
HDAC4 P56524 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967038 0.98 POLB (0.42) FAAHTRPV1POLBL3MBTL1KDM4E
SCHEMBL14968235 0.95 POLB (0.42) FAAHTRPV1POLBL3MBTL1KDM4E
SCHEMBL14967781 0.91 FAAH (0.40) FAAHTRPV1POLBL3MBTL1KDM4E
SCHEMBL14969500 0.90 FAAH (0.52) FAAHTRPV1POLBL3MBTL1KDM4E
SCHEMBL14967804 0.89 POLB (0.40) FAAHTRPV1POLBL3MBTL1KDM4E
SCHEMBL14967817 0.88 FAAH (0.50) FAAHTRPV1POLBL3MBTL1KDM4E
SCHEMBL14967569 0.86 POLB (0.40) FAAHTRPV1POLBL3MBTL1KDM4E
SCHEMBL14968020 0.85 FAAH (0.47) FAAHTRPV1POLBL3MBTL1KDM4E
SCHEMBL14967505 0.84 MEN1 (0.45) FAAHTRPV1L3MBTL1KDM4EAKR1C1
SCHEMBL14968268 0.82 MEN1 (0.46) L3MBTL1AKR1C1HDAC4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed