Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.67 |
| ▸ | POLB | P06746 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 7/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496616 | 0.79 | MEN1 (0.58) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL1455735 | 0.79 | KMT2A (1.00) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL10817708 | 0.79 | POLB (0.68) | MEN1KMT2APOLBALDH1A1HTT | |
| SCHEMBL9843646 | 0.78 | LMNA (0.66) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL6593159 | 0.77 | LMNA (0.68) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL6769086 | 0.77 | LMNA (0.64) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL1496783 | 0.76 | MEN1 (0.54) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL5182303 | 0.75 | LMNA (0.69) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL3792013 | 0.74 | LMNA (0.64) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL15562567 | 0.74 | LMNA (0.64) | MEN1KMT2APOLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023722-A1 | NOVEL QUINOXALINONE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2011-03-03 | — | — | WO | disclosed |