SCHEMBL14967906

SCHEMBL14967906

CCCOC(=O)C1(C)OC1CC

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.33
PTPN1 P18031 1/20 0.33
PPP1CC P36873 1/20 0.33
HCAR2 Q8TDS4 1/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.31
KDM4E B2RXH2 1/20 0.30
GLA P06280 1/20 0.30
ESR1 P03372 1/20 0.30
CHRM1 P11229 1/20 0.30
TSHR P16473 1/20 0.30
SLC6A2 P23975 1/20 0.30
KDR P35968 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967674 0.89 ALDH1A1 (0.42) HCAR2ALDH1A1LMNAESR1TSHR
SCHEMBL14968118 0.88 NAAA (0.42) HCAR2ALDH1A1LMNATSHR
SCHEMBL14967778 0.86 NAAA (0.44) HCAR2ALDH1A1LMNATSHR
SCHEMBL7175636 0.85 ALDH1A1 (0.36) ALDH1A1LMNAKDM4EGLATSHR
SCHEMBL14967910 0.81 HCAR2 (0.34) PPM1BPTPN1PPP1CCHCAR2ALDH1A1
SCHEMBL1199784 0.79 IDO1 (0.30)
SCHEMBL14967764 0.76 PPM1B (0.32) PPM1BPTPN1PPP1CCHCAR2ALDH1A1
SCHEMBL14968347 0.74 TSHR (0.32) ALDH1A1LMNAKDM4ETSHR
SCHEMBL14968046 0.74 HCRTR2 (0.32)
SCHEMBL14967021 0.73 EPHX1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed