SCHEMBL14967910

SCHEMBL14967910

CCCOC(=O)C1(C)OC1C

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.34
PPM1B O75688 1/20 0.34
PTPN1 P18031 1/20 0.34
PPP1CC P36873 1/20 0.34
ALDH1A1 P00352 3/20 0.33
LMNA P02545 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GLA P06280 1/20 0.32
ESR1 P03372 1/20 0.32
CHRM1 P11229 1/20 0.32
TSHR P16473 1/20 0.32
SLC6A2 P23975 1/20 0.32
KDR P35968 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14968017 0.89 ALDH1A1 (0.45) HCAR2ALDH1A1LMNAESR1TSHR
SCHEMBL14968116 0.87 NAAA (0.44) HCAR2ALDH1A1GLATSHR
SCHEMBL7061157 0.83 ALDH1A1 (0.39) ALDH1A1LMNAKDM4EGLA
SCHEMBL14967906 0.81 PPM1B (0.33) HCAR2PPM1BPTPN1PPP1CCALDH1A1
SCHEMBL14967651 0.72 LMNA (0.45) ALDH1A1LMNAKDM4ETSHR
SCHEMBL9692331 0.72
SCHEMBL16109753 0.71 ALDH1A1 (0.35) ALDH1A1LMNAKDM4EESR1CHRM1
SCHEMBL14968301 0.71 HCAR2 (0.36) HCAR2PPM1BPTPN1PPP1CCALDH1A1
SCHEMBL14967674 0.71 ALDH1A1 (0.42) HCAR2ALDH1A1LMNAESR1TSHR
SCHEMBL14967349 0.69 PPM1B (0.42) HCAR2PPM1BPTPN1PPP1CCALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed