SCHEMBL14968229

SCHEMBL14968229

CCN1CCN(S(=O)(=O)c2cccs2)CC1

nearest known ligand 0.75

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PKM P14618 5/20 0.75
RAB9A P51151 3/20 0.65
NPC1 O15118 2/20 0.62
LMNA P02545 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
ALDH1A1 P00352 2/20 0.59
MAPT P10636 3/20 0.57
TSHR P16473 3/20 0.57
GAA P10253 1/20 0.57
USP2 O75604 1/20 0.57
KDM4E B2RXH2 1/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
JAK2 O60674 1/20 0.56
MAPK1 P28482 2/20 0.56
NPSR1 Q6W5P4 1/20 0.55
POLB P06746 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7531705 0.84 PKM (0.75) PKMRAB9ANPC1LMNASMN1; SMN2
SCHEMBL14314685 0.84 PKM (0.65) PKMRAB9ANPC1LMNASMN1; SMN2
SCHEMBL12726891 0.84 PKM (0.69) PKMRAB9ANPC1LMNASMN1; SMN2
SCHEMBL14314684 0.83 PKM (0.63) PKMRAB9ANPC1LMNASMN1; SMN2
SCHEMBL2888089 0.83 PKM (0.63) PKMRAB9ANPC1LMNASMN1; SMN2
SCHEMBL9597683 0.82 RAB9A (0.73) PKMRAB9ANPC1LMNASMN1; SMN2
SCHEMBL9597306 0.82 PKM (0.71) PKMRAB9ANPC1LMNASMN1; SMN2
SCHEMBL27748352 0.82 PKM (0.71) PKMRAB9ANPC1LMNASMN1; SMN2
SCHEMBL19002724 0.80 MEN1 (0.68) PKMRAB9ANPC1LMNAALDH1A1
SCHEMBL5415687 0.80 PKM (0.85) PKMRAB9ANPC1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240174867-A1 CORROSION INHIBITING COATING COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2024-05-30 US claimed
EP-4301817-A1 CORROSION INHIBITING COATING COMPOSITIONS PRC-Desoto International, Inc. (US) 2024-01-10 EP claimed
CN-117321150-A Corrosion inhibiting coating composition PRC-迪索托国际公司 2023-12-29 CN claimed
WO-2022187845-A1 CORROSION INHIBITING COATING COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2022-09-09 WO claimed
US-12577412-B2 Corrosion inhibiting coating compositions PRC-DESOTO INTERNATIONAL, INC. (US) 2026-03-17 US disclosed
WO-2025151695-A1 COATING COMPOSITIONS COMPRISING MAGNESIUM OXIDE AND A LITHIUM COMPOUND PRC-DESOTO INTERNATIONAL, INC. (US) 2025-07-17 WO disclosed
US-20240174867-A1 CORROSION INHIBITING COATING COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2024-05-30 US disclosed
EP-4301817-A1 CORROSION INHIBITING COATING COMPOSITIONS PRC-Desoto International, Inc. (US) 2024-01-10 EP disclosed
CN-117321150-A Corrosion inhibiting coating composition PRC-迪索托国际公司 2023-12-29 CN disclosed
WO-2022187845-A1 CORROSION INHIBITING COATING COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2022-09-09 WO disclosed
US-8993563-B2 Phosphoinositide 3-kinase inhibitor compounds and methods of use GENENTECH, INC. (US) 2015-03-31 US disclosed
US-20130129820-A1 PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND METHODS OF USE GENENTECH, INC. (US) 2013-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130129820-A1 PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND METHODS OF USE PIK3CA, AKT3, PI4KA PKM 361/4885RAB9A 986/4885NPC1 991/4885
US-12577412-B2 Corrosion inhibiting coating compositions MGMT, MBD2, MECP2 PKM 2270/4885RAB9A 2485/4885NPC1 3972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.