Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 6/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531705 | 0.82 | PKM (0.75) | PKMRAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL14968229 | 0.82 | PKM (0.75) | PKMRAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL28777020 | 0.79 | HTT (0.58) | SMN1; SMN2ALDH1A1GAAKDM4EHTT | |
| SCHEMBL9597306 | 0.79 | PKM (0.71) | PKMRAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL12726891 | 0.78 | PKM (0.69) | PKMRAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL13974920 | 0.78 | RAB9A (0.64) | PKMRAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL5415687 | 0.77 | PKM (0.85) | PKMRAB9ASMN1; SMN2TSHRNPSR1 | |
| SCHEMBL9597683 | 0.77 | RAB9A (0.73) | PKMRAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL12656171 | 0.76 | PKM (0.77) | PKMRAB9ASMN1; SMN2TSHRNPSR1 | |
| SCHEMBL5830802 | 0.76 | PKM (0.77) | PKMRAB9ATSHRNPC1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101479274-A | Pharmaceutical compounds | HOFFMANN LA ROCHE (CH) | 2009-07-08 | — | — | CN | disclosed |