SCHEMBL1496832

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1496841	0.96	RAB9A (0.39)	GAARAB9ANPC1SMN1; SMN2KMT2A
	SCHEMBL1497019	0.96	NPC1 (0.40)	GAARAB9ANPC1SMN1; SMN2KMT2A
	SCHEMBL3232276	0.94	GAA (0.44)	GAARAB9ANPC1SMN1; SMN2KMT2A
	SCHEMBL1482175	0.91	RAB9A (0.40)	RAB9ANPC1SMN1; SMN2KMT2AROCK2
	SCHEMBL3221320	0.89	RAB9A (0.40)	GAARAB9ANPC1SMN1; SMN2KMT2A
	SCHEMBL3226141	0.88	PDCD1 (0.41)	GAARAB9ANPC1SMN1; SMN2KMT2A
	SCHEMBL1496949	0.88	TP53 (0.42)	GAARAB9ANPC1SMN1; SMN2KMT2A
	SCHEMBL1497123	0.88	GAA (0.46)	GAARAB9ANPC1SMN1; SMN2KMT2A
	SCHEMBL11892993	0.88	ROCK2 (0.39)	RAB9AKMT2AROCK2CYP3A4CYP2D6
	SCHEMBL3233969	0.87	PDCD1 (0.41)	GAARAB9ANPC1SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.