SCHEMBL1496859

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1496879	0.95	CSF1R (0.36)	AVPR1ASLC2A1ATMCSF1RFLT3
	SCHEMBL1496870	0.94	AVPR1A (0.37)	AVPR1ASLC2A1USP2CSF1RFLT3
	SCHEMBL3233856	0.93	AVPR1A (0.42)	AVPR1ASLC2A1USP2MCHR1ABL1
	SCHEMBL1496873	0.93	USP2 (0.44)	ATMUSP2HRH3ROCK2TSHR
	SCHEMBL1497074	0.91	USP2 (0.42)	ATMUSP2HRH3ROCK2TSHR
	SCHEMBL8007884	0.90	USP2 (0.40)	AVPR1AUSP2CSF1RFLT3ABL1
	SCHEMBL1497087	0.89	SLC2A1 (0.41)	AVPR1ASLC2A1USP2CSF1RFLT3
	SCHEMBL1496887	0.89	HDAC1 (0.40)	AVPR1AUSP2CSF1RFLT3ABL1
	SCHEMBL3233734	0.89	MCHR1 (0.39)	AVPR1ACSF1RFLT3MCHR1HRH3
	SCHEMBL11892997	0.88	AVPR1A (0.36)	AVPR1ASLC2A1USP2CSF1RFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.