SCHEMBL1496887

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1496851	0.93	USP2 (0.45)	HDAC1HDAC6USP2MEN1KMT2A
	SCHEMBL11892984	0.92	FGFR1 (0.35)	USP2FGFR1MEN1KMT2ASIGMAR1
	SCHEMBL1496941	0.92	SIGMAR1 (0.43)	USP2FGFR1SIGMAR1ACKR3AVPR1A
	SCHEMBL1496922	0.91	USP2 (0.43)	HDAC1HDAC6USP2MEN1KMT2A
	SCHEMBL1496980	0.90	SIGMAR1 (0.40)	USP2SIGMAR1ACKR3AVPR1A
	SCHEMBL8007884	0.89	USP2 (0.40)	USP2MEN1KMT2AMAPTKDM4E
	SCHEMBL1496859	0.89	AVPR1A (0.38)	USP2CSF1RFLT3AVPR1AABL1
	SCHEMBL1496870	0.88	AVPR1A (0.37)	USP2FGFR1MEN1KMT2AMAPT
	SCHEMBL1497016	0.88	USP2 (0.43)	HDAC1HDAC6USP2MEN1KMT2A
	SCHEMBL8004877	0.87	HDAC1 (0.42)	HDAC1HDAC6USP2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.