SCHEMBL1496879

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1496859	0.95	AVPR1A (0.38)	CSF1RFLT3MCHR1HRH3ABL1
	SCHEMBL3233734	0.93	MCHR1 (0.39)	CSF1RFLT3MCHR1HRH3ABL1
	SCHEMBL8001252	0.89	CSF1R (0.38)	CSF1RFLT3MCHR1ABL1SRC
	SCHEMBL1496870	0.89	AVPR1A (0.37)	CSF1RFLT3ABL1SRCMEN1
	SCHEMBL1496831	0.89	KDM4E (0.38)	CSF1RFLT3MCHR1HRH3ABL1
	SCHEMBL3233856	0.89	AVPR1A (0.42)	MCHR1ABL1SRCPDCD1CD274
	SCHEMBL1496873	0.88	USP2 (0.44)	HRH3ATMCD274ROCK2MEN1
	SCHEMBL1497074	0.88	USP2 (0.42)	HRH3ATMCD274ROCK2MEN1
	SCHEMBL1496943	0.86	KCNH2 (0.38)	CSF1RFLT3MCHR1HRH3MAPK14
	SCHEMBL1497091	0.86	TRPA1 (0.38)	MCHR1HRH3TRPA1PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.