SCHEMBL1496868

SCHEMBL1496868

O=CC(Cc1ccccc1)=NOC(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 2/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
NPC1 O15118 6/20 0.44
RAB9A P51151 6/20 0.44
PKM P14618 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
MAPT P10636 2/20 0.44
CDK5 Q00535 3/20 0.42
CDK5R1 Q15078 3/20 0.42
MITF O75030 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42
TNF P01375 1/20 0.41
KLF5 Q13887 1/20 0.41
NOD1 Q9Y239 1/20 0.41
MIF P14174 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30552406 0.83 SMN1; SMN2 (0.47) PLA2G7KMT2ANPC1RAB9APKM
SCHEMBL29620218 0.78 SMN1; SMN2 (0.53) SLC6A2SLC6A3KMT2ATDP1NPC1
SCHEMBL28907502 0.76 CES2 (0.49) PLA2G7KMT2ATDP1NPC1RAB9A
SCHEMBL27893429 0.76 CES2 (0.49) PLA2G7KMT2ATDP1NPC1RAB9A
SCHEMBL28249199 0.76 CES2 (0.49) PLA2G7KMT2ATDP1NPC1RAB9A
SCHEMBL25216770 0.73 SMN1; SMN2 (0.56) PLA2G7KMT2ANPC1RAB9APKM
SCHEMBL6574736 0.72 CTBP2 (0.52) KMT2AL3MBTL1
SCHEMBL92081 0.70 NPC1 (0.56) PLA2G7KMT2ANPC1RAB9APKM
(Diphenylmethylidene)Amino Benzoate SCHEMBL92010 0.70 ALDH1A1 (0.66) PLA2G7KMT2ANPC1RAB9APKM
SCHEMBL27532422 0.70 NPC1 (0.61) PLA2G7TDP1NPC1RAB9APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2633569-A1 MULTILAYERED PROTECTIVE LAYER, ORGANIC OPTO-ELECTRIC DEVICE AND METHOD OF MANUFACTURING THE SAME Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) 2013-09-04 EP disclosed
EP-2475467-A1 COATING METHOD AND COATING APPARATUS Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO (NL) 2012-07-18 EP disclosed
WO-2012057618-A1 MULTILAYERED PROTECTIVE LAYER, ORGANIC OPTO-ELECTRIC DEVICE AND METHOD OF MANUFACTURING THE SAME NEDERLANDSE ORGANISATIE VOOR TOEGEPAST- NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2012-05-03 WO disclosed
WO-2011028119-A1 COATING METHOD AND COATING APPARATUS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2011-03-10 WO disclosed
EP-1680712-A1 PHOTOCURABLE COMPOSITION FOR PRODUCING CURED ARTICLES HAVING HIGH CLARITY AND IMPROVED MECHANICAL PROPERTIES Huntsman Advanced Materials (Switzerland) GmbH (CH) 2006-07-19 EP disclosed
WO-2005045523-A1 PHOTOCURABLE COMPOSITION FOR PRODUCING CURED ARTICLES HAVING HIGH CLARITY AND IMPROVED MECHANICAL PROPERTIES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2005-05-19 WO disclosed
EP-1497696-A2 PHOTOCURABLE COMPOSITIONS CONTAINING REACTIVE PARTICLES Huntsman Advanced Materials (Switzerland) GmbH (CH) 2005-01-19 EP disclosed
WO-2003089991-A2 PHOTOCURABLE COMPOSITIONS CONTAINING REACTIVE PARTICLES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2003-10-30 WO disclosed
EP-0807265-A1 CROSSLINKED POLYMERS Novartis AG (CH) 1997-11-19 EP disclosed
EP-0807266-A1 CROSSLINKED POLYMERS CONTAINING SALT STRUCTURES Novartis AG (CH) 1997-11-19 EP disclosed
WO-1996024074-A1 CROSSLINKED POLYMERS NOVARTIS AG (CH) 1996-08-08 WO disclosed
WO-1996024078-A1 CROSSLINKED POLYMERS CONTAINING SALT STRUCTURES NOVARTIS AG (CH) 1996-08-08 WO disclosed
US-5474876-A Carboxyl-containing polymeric precursor of heterocyclic polymer which is stable at high temperatures and soluble in polar solvents, copolymerizable unsaturated tertiary sulfonium salt, photoinitiator, polar aprotic organic solvent BASF LACKE + FARBEN AG (DE) 1995-12-12 US disclosed