SCHEMBL1496883

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3829603	0.92	RAB9A (0.44)	TRPV1RAB9ANPC1SMN1; SMN2PKM
	SCHEMBL1482175	0.90	RAB9A (0.40)	TRPV1RAB9ANPC1SMN1; SMN2PKM
	SCHEMBL3834327	0.88	HDAC1 (0.48)	TRPV1RAB9ANPC1SMN1; SMN2PKM
	SCHEMBL2479972	0.88	NPSR1 (0.47)	RAB9ANPC1SMN1; SMN2PKMMEN1
	SCHEMBL7998011	0.87	ALDH1A1 (0.49)	RAB9ANPC1SMN1; SMN2TP53MEN1
	SCHEMBL8002146	0.86	RAB9A (0.45)	RAB9ANPC1SMN1; SMN2PKMTP53
	SCHEMBL1496841	0.86	RAB9A (0.39)	TRPV1RAB9ANPC1SMN1; SMN2PKM
	SCHEMBL1497019	0.86	NPC1 (0.40)	RAB9ANPC1SMN1; SMN2PKMTP53
	SCHEMBL3832579	0.85	RAB9A (0.42)	TRPV1RAB9ANPC1SMN1; SMN2PKM
	SCHEMBL8004784	0.84	HDAC1 (0.40)	ROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.