Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | EEF2K | O00418 | 4/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 4/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | EEF2 | P13639 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14969053 | 0.82 | EEF2K (0.41) | IKBKBEEF2KRCE1KDM4EALDH1A1 | |
| SCHEMBL14969095 | 0.82 | ENPP1 (0.40) | IKBKBEEF2KRCE1KDM4EALDH1A1 | |
| SCHEMBL14969185 | 0.82 | RCE1 (0.38) | IKBKBEEF2KRCE1KDM4EALDH1A1 | |
| SCHEMBL14966496 | 0.79 | KDM4E (0.38) | IKBKBEEF2KRCE1KDM4EALDH1A1 | |
| SCHEMBL14966299 | 0.73 | RCE1 (0.44) | IKBKBEEF2KRCE1KDM4EALDH1A1 | |
| SCHEMBL14969004 | 0.70 | IKBKB (0.36) | IKBKBEEF2KRCE1KDM4EALDH1A1 | |
| SCHEMBL14969024 | 0.70 | RCE1 (0.36) | IKBKBEEF2KRCE1KDM4EALDH1A1 | |
| SCHEMBL14968997 | 0.69 | EEF2K (0.37) | IKBKBEEF2KRCE1KDM4EALDH1A1 | |
| SCHEMBL14968912 | 0.69 | RCE1 (0.38) | IKBKBEEF2KRCE1KDM4EALDH1A1 | |
| SCHEMBL24755247 | 0.69 | SLC9A1 (0.50) | IKBKBEEF2KRCE1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072882-A1 | 2 -AMINO- 1, 8 -NAPHTHYRIDINE-3 -CARBOXAMIDE DERIVATIVES AS ANTIMICROBIAL AGENTS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072882-A1 | 2 -AMINO- 1, 8 -NAPHTHYRIDINE-3 -CARBOXAMIDE DERIVATIVES AS ANTIMICROBIAL AGENTS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-23 | — | — | WO | disclosed |