Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 4/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | EEF2 | P13639 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CD38 | P28907 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14969003 | 0.79 | RCE1 (0.44) | EEF2KRCE1ALDH1A1GAAHSD17B10 | |
| SCHEMBL14969053 | 0.72 | EEF2K (0.41) | EEF2KRCE1ALDH1A1GAAEEF2 | |
| SCHEMBL14966496 | 0.69 | KDM4E (0.38) | EEF2KRCE1ALDH1A1GAAEEF2 | |
| SCHEMBL14966299 | 0.69 | RCE1 (0.44) | EEF2KRCE1ALDH1A1GAAEEF2 | |
| SCHEMBL14968947 | 0.69 | IKBKB (0.39) | EEF2KRCE1ALDH1A1GAAEEF2 | |
| SCHEMBL14968935 | 0.67 | EEF2K (0.46) | EEF2KRCE1ALDH1A1GAAEEF2 | |
| SCHEMBL20298365 | 0.65 | POLB (0.49) | EEF2KRCE1ALDH1A1GAAKDM4E | |
| SCHEMBL9287278 | 0.65 | NPSR1 (0.51) | ALDH1A1GAAHSD17B10NPSR1KDM4E | |
| SCHEMBL14968912 | 0.64 | RCE1 (0.38) | EEF2KRCE1ALDH1A1GAANPSR1 | |
| SCHEMBL20321443 | 0.63 | EEF2K (0.44) | EEF2KRCE1ALDH1A1GAAEEF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072882-A1 | 2 -AMINO- 1, 8 -NAPHTHYRIDINE-3 -CARBOXAMIDE DERIVATIVES AS ANTIMICROBIAL AGENTS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-23 | — | — | WO | disclosed |