Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CD38 | P28907 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14968997 | 0.79 | EEF2K (0.37) | RCE1IKBKBNPSR1ALDH1A1HPGD | |
| SCHEMBL27824628 | 0.71 | RCE1 (0.49) | RCE1IKBKBPLA2G2ANPSR1ALDH1A1 | |
| SCHEMBL14969053 | 0.70 | EEF2K (0.41) | RCE1IKBKBSIRT1ALDH1A1HPGD | |
| SCHEMBL5434583 | 0.69 | DHFR (0.47) | NPSR1ADCY10CDC7 | |
| SCHEMBL6415745 | 0.69 | NPSR1 (0.68) | PLA2G2ANPSR1ALDH1A1HPGDKDM4E | |
| SCHEMBL12277345 | 0.69 | KMT2A (0.46) | PLA2G2AALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL14967093 | 0.68 | KDM4E (0.51) | NPSR1ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL14968935 | 0.68 | EEF2K (0.46) | RCE1IKBKBALDH1A1HPGDCD38 | |
| SCHEMBL14966496 | 0.68 | KDM4E (0.38) | RCE1IKBKBALDH1A1HPGDKDM4E | |
| SCHEMBL14968947 | 0.67 | IKBKB (0.39) | RCE1IKBKBALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072882-A1 | 2 -AMINO- 1, 8 -NAPHTHYRIDINE-3 -CARBOXAMIDE DERIVATIVES AS ANTIMICROBIAL AGENTS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072882-A1 | 2 -AMINO- 1, 8 -NAPHTHYRIDINE-3 -CARBOXAMIDE DERIVATIVES AS ANTIMICROBIAL AGENTS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-23 | — | — | WO | disclosed |