Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 4/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | PRKACG | P22612 | 1/20 | 0.40 |
| ▸ | PRKACB | P22694 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14968934 | 0.81 | CDK8 (0.40) | EEF2KRCE1IKBKBKDM4EALDH1A1 | |
| SCHEMBL14966299 | 0.74 | RCE1 (0.44) | EEF2KRCE1IKBKBKDM4EALDH1A1 | |
| SCHEMBL9696617 | 0.72 | IKBKB (0.49) | EEF2KRCE1POLBIKBKBKDM4E | |
| SCHEMBL20298365 | 0.69 | POLB (0.49) | EEF2KRCE1POLBIKBKBKDM4E | |
| SCHEMBL14968912 | 0.69 | RCE1 (0.38) | EEF2KRCE1IKBKBKDM4EALDH1A1 | |
| SCHEMBL147683 | 0.68 | POLB (0.67) | POLBIKBKBKDM4EALDH1A1HPGD | |
| SCHEMBL31295740 | 0.68 | POLB (0.67) | POLBIKBKBKDM4EALDH1A1HPGD | |
| SCHEMBL14968947 | 0.68 | IKBKB (0.39) | EEF2KRCE1POLBIKBKBKDM4E | |
| SCHEMBL14969024 | 0.67 | RCE1 (0.36) | EEF2KRCE1IKBKBKDM4EALDH1A1 | |
| SCHEMBL14966609 | 0.67 | IKBKB (0.41) | EEF2KRCE1IKBKBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072882-A1 | 2 -AMINO- 1, 8 -NAPHTHYRIDINE-3 -CARBOXAMIDE DERIVATIVES AS ANTIMICROBIAL AGENTS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072882-A1 | 2 -AMINO- 1, 8 -NAPHTHYRIDINE-3 -CARBOXAMIDE DERIVATIVES AS ANTIMICROBIAL AGENTS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-23 | — | — | WO | disclosed |