Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 7/20 | 0.42 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31250439 | 0.94 | KLK5 (0.43) | GAACTSKCTSSCTSLCTSB | |
| SCHEMBL9813244 | 0.88 | CTSK (0.42) | GAACTSKCTSSCTSLCTSB | |
| SCHEMBL9481477 | 0.88 | CTSK (0.42) | GAACTSKCTSSCTSLCTSB | |
| SCHEMBL8752932 | 0.86 | GAA (0.44) | GAACTSKCTSSCTSLCTSB | |
| SCHEMBL9114796 | 0.86 | GAA (0.44) | GAACTSKCTSSCTSLCTSB | |
| SCHEMBL25094921 | 0.85 | GAA (0.43) | GAACTSKCTSSCTSLCTSB | |
| SCHEMBL9111680 | 0.84 | GAA (0.43) | GAACTSKCTSSAKT1MALT1 | |
| SCHEMBL8752900 | 0.84 | GAA (0.43) | GAACTSKCTSSAKT1MALT1 | |
| SCHEMBL8752885 | 0.84 | SYK (0.45) | GAACTSKCTSSCTSLCTSB | |
| SCHEMBL5033293 | 0.81 | MMP2 (0.46) | CTSKCTSSAKT1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072882-A1 | 2 -AMINO- 1, 8 -NAPHTHYRIDINE-3 -CARBOXAMIDE DERIVATIVES AS ANTIMICROBIAL AGENTS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-23 | — | — | WO | disclosed |