SCHEMBL1496923

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1497008	0.96	ALDH1A1 (0.39)	TSHRUSP2MAPTLMNAALDH1A1
	SCHEMBL1497136	0.95	PIR (0.42)	TSHRUSP2MAPTLMNAALDH1A1
	SCHEMBL8000742	0.95	USP2 (0.47)	TSHRUSP2MAPTLMNAALDH1A1
	SCHEMBL3232015	0.94	TSHR (0.43)	TSHRUSP2MAPTLMNAALDH1A1
	SCHEMBL1496838	0.93	USP2 (0.45)	TSHRUSP2MAPTLMNAALDH1A1
	SCHEMBL1496949	0.92	TP53 (0.42)	TSHRMAPTLMNAALDH1A1KDM4E
	SCHEMBL1496847	0.91	PIR (0.40)	USP2MAPTLMNAALDH1A1KDM4E
	SCHEMBL1496959	0.91	ALDH1A1 (0.43)	TSHRUSP2MAPTLMNAALDH1A1
	SCHEMBL3226024	0.90	ALDH1A1 (0.41)	TSHRMAPTLMNAALDH1A1KDM4E
	SCHEMBL1496841	0.89	RAB9A (0.39)	MAPTLMNAALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.