SCHEMBL1497006

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1496927	0.89	RAB9A (0.37)	MAPTTP53LMNASMN1; SMN2ALDH1A1
	SCHEMBL1496937	0.88	ALDH1A1 (0.37)	MAPTTHRBLMNASMN1; SMN2ALDH1A1
	SCHEMBL3835296	0.85	ALDH1A1 (0.41)	MAPTTP53LMNASMN1; SMN2ALDH1A1
	SCHEMBL1496908	0.85	ALDH1A1 (0.41)	MAPTLMNASMN1; SMN2ALDH1A1MEN1
	SCHEMBL1496847	0.84	PIR (0.40)	MAPTTP53THRBLMNASMN1; SMN2
	SCHEMBL1482175	0.83	RAB9A (0.40)	MAPTLMNASMN1; SMN2ALDH1A1MEN1
	SCHEMBL13374699	0.83	ALDH1A1 (0.35)	MAPTLMNASMN1; SMN2ALDH1A1MEN1
	SCHEMBL1497136	0.83	PIR (0.42)	MAPTTP53LMNASMN1; SMN2ALDH1A1
	SCHEMBL1497008	0.82	ALDH1A1 (0.39)	MAPTTP53THRBLMNASMN1; SMN2
	SCHEMBL1496959	0.82	ALDH1A1 (0.43)	MAPTTP53THRBLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.