SCHEMBL1497023

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1496966	0.96	TSHR (0.41)	ALDH1A1GAALMNATHRBRAB9A
	SCHEMBL7999000	0.94	ALDH1A1 (0.42)	ALDH1A1GAALMNATHRBMAPK1
	SCHEMBL1497032	0.93	ALDH1A1 (0.47)	ALDH1A1GAALMNATHRBMAPK1
	SCHEMBL4217909	0.91	ALDH1A1 (0.43)	ALDH1A1GAALMNATHRBMAPK1
	SCHEMBL8004427	0.90	USP2 (0.41)	ALDH1A1LMNARAB9ANPC1PKM
	SCHEMBL1496986	0.89	USP2 (0.47)	ALDH1A1GAALMNATHRBMAPK1
	SCHEMBL1496911	0.89	USP2 (0.44)	ALDH1A1GAALMNATHRBMAPK1
	SCHEMBL1497008	0.88	ALDH1A1 (0.39)	ALDH1A1GAALMNATHRBMAPK1
	SCHEMBL1484237	0.88	RAB9A (0.42)	ALDH1A1LMNAMAPK1RAB9ANPC1
	SCHEMBL1496929	0.87	ALDH1A1 (0.39)	ALDH1A1GAALMNATHRBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.