Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.86 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.75 |
| ▸ | MEN1 | O00255 | 3/20 | 0.75 |
| ▸ | PKM | P14618 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HRH1 | P35367 | 2/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | DRD5 | P21918 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012697 | 0.98 | KDM4E (0.84) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL14970455 | 0.91 | KDM4E (0.88) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL11020028 | 0.89 | ALDH1A1 (0.85) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL28311408 | 0.85 | KDM4E (0.75) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL20360543 | 0.84 | KDM4E (0.64) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL21616844 | 0.84 | KDM4E (0.67) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL14970717 | 0.84 | KDM4E (0.88) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL9241445 | 0.82 | KDM4E (0.61) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL7962009 | 0.81 | KDM4E (0.60) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL10673959 | 0.80 | ALDH1A1 (0.69) | KDM4ESMN1; SMN2ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |