Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.88 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.88 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.88 |
| ▸ | LMNA | P02545 | 5/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.75 |
| ▸ | MEN1 | O00255 | 3/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | HTR1A | P08908 | 3/20 | 0.62 |
| ▸ | HTR7 | P34969 | 3/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012697 | 0.85 | KDM4E (0.84) | KDM4EALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL14970458 | 0.84 | KDM4E (0.86) | KDM4EALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL24322736 | 0.82 | LMNA (0.63) | KDM4EALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL24324263 | 0.82 | LMNA (0.63) | KDM4EALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL23366615 | 0.81 | KDM4E (0.61) | KDM4EALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL28311408 | 0.81 | KDM4E (0.75) | KDM4EALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL5388793 | 0.80 | HRH3 (0.71) | KDM4EALDH1A1SMN1; SMN2LMNAHRH3 | |
| SCHEMBL15331415 | 0.80 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL21750486 | 0.80 | KDM4E (0.70) | KDM4EALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL17848618 | 0.78 | HTR1A (0.61) | KDM4EALDH1A1SMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |