Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 7/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.39 |
| ▸ | PRKX | P51817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1497059 | 0.91 | UTS2R (0.47) | UTS2RALDH1A1HPGD | |
| SCHEMBL1496897 | 0.89 | UTS2R (0.47) | UTS2RROCK2ROCK1ATG4BANPEP | |
| SCHEMBL1497004 | 0.89 | UTS2R (0.62) | UTS2RROCK2ALDH1A1ROCK1 | |
| SCHEMBL1496907 | 0.88 | UTS2R (0.45) | UTS2RROCK2ALDH1A1ROCK1ATG4B | |
| Hydrochloric Acid SCHEMBL1497060 | 0.85 | UTS2R (0.47) | UTS2RROCK2ALDH1A1ROCK1KMT2A | |
| SCHEMBL1496971 | 0.85 | UTS2R (0.43) | UTS2RROCK2ALDH1A1KDM4EHPGD | |
| SCHEMBL1497206 | 0.85 | UTS2R (0.46) | UTS2RMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1496948 | 0.84 | UTS2R (0.47) | UTS2RROCK2ROCK1 | |
| SCHEMBL1497073 | 0.84 | UTS2R (0.47) | UTS2RANPEPMEN1GAAKMT2A | |
| SCHEMBL1496910 | 0.83 | UTS2R (0.41) | UTS2RROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292611-B1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-07-25 | — | — | EP | disclosed |
| EP-2292611-A1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2011-03-09 | — | — | EP | disclosed |