SCHEMBL14970675

SCHEMBL14970675

Clc1cccc(OCCN2CCCCCC2)c1

nearest known ligand 0.85

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.85
LMNA P02545 1/20 0.85
MAPK1 P28482 1/20 0.85
HTT P42858 1/20 0.85
HRH3 Q9Y5N1 8/20 0.81
KMT2A Q03164 2/20 0.74
MEN1 O00255 1/20 0.74
CYP2D6 P10635 1/20 0.72
LTA4H P09960 2/20 0.67
BACE1 P56817 1/20 0.67
KDM4E B2RXH2 3/20 0.64
ALDH1A1 P00352 2/20 0.64
TP53 P04637 1/20 0.64
TSHR P16473 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL14966290 0.98 SMN1; SMN2 (0.82) SMN1; SMN2LMNAMAPK1HTTHRH3
SCHEMBL491593 0.88 HRH3 (0.97) SMN1; SMN2LMNAMAPK1HTTHRH3
SCHEMBL5856321 0.87 HRH3 (0.94) SMN1; SMN2LMNAMAPK1HTTHRH3
SCHEMBL6932153 0.82 KDM4E (0.72) SMN1; SMN2LMNAMAPK1HTTHRH3
SCHEMBL8693202 0.81 LMNA (0.74) SMN1; SMN2LMNAMAPK1HTTHRH3
SCHEMBL7138782 0.81 LTA4H (0.79) SMN1; SMN2LMNAMAPK1HTTHRH3
SCHEMBL15196314 0.81 BACE1 (0.67) SMN1; SMN2LMNAMAPK1HTTHRH3
SCHEMBL17177129 0.81 KDM4E (0.84) SMN1; SMN2LMNAMAPK1HTTHRH3
SCHEMBL259391 0.81 KDM4E (0.86) SMN1; SMN2HTTHRH3LTA4HBACE1
SCHEMBL15474805 0.81 HRH3 (0.76) SMN1; SMN2HTTHRH3KMT2ALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013074965-A1 AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS MICROBIOTIX, INC. (US) 2013-05-23 WO disclosed