Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | NR1D1 | P20393 | 7/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14971116 | 0.85 | MITF (0.41) | MITFNR1D1NR1H3LMNA | |
| SCHEMBL14965930 | 0.83 | MITF (0.43) | MITFNR1D1NR1H3LMNAALDH1A1 | |
| SCHEMBL14971120 | 0.82 | MITF (0.38) | MITFLMNAALDH1A1 | |
| SCHEMBL14971049 | 0.81 | MITF (0.41) | MITFLMNAALDH1A1 | |
| SCHEMBL14971139 | 0.81 | LMNA (0.38) | MITFLMNAALDH1A1 | |
| SCHEMBL14971141 | 0.80 | NR1D1 (0.37) | MITFNR1D1NR1H3LMNAALDH1A1 | |
| SCHEMBL14971131 | 0.79 | MITF (0.35) | MITFLMNAALDH1A1 | |
| SCHEMBL14971143 | 0.78 | NR1D1 (0.35) | MITFNR1D1LMNAALDH1A1 | |
| SCHEMBL14971154 | 0.78 | MITF (0.34) | MITFLMNAALDH1A1 | |
| SCHEMBL14971142 | 0.78 | KCNH2 (0.39) | MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |