Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 8/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149716 | 0.78 | TSHR (0.40) | TSHRALDH1A1 | |
| SCHEMBL11527206 | 0.75 | ALDH1A1 (0.41) | POLBTSHRALDH1A1KDM4EMAPT | |
| SCHEMBL3320292 | 0.73 | TSHR (0.36) | TSHRALDH1A1KDM4E | |
| SCHEMBL11738114 | 0.72 | TSHR (0.33) | TSHR | |
| SCHEMBL11738612 | 0.69 | TSHR (0.33) | TSHR | |
| SCHEMBL11772571 | 0.69 | ALDH1A1 (0.49) | TSHRALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL4059532 | 0.69 | TSHR (0.47) | TSHRALDH1A1MAPT | |
| SCHEMBL23810922 | 0.69 | TSHR (0.39) | POLBTSHRALDH1A1 | |
| SCHEMBL328790 | 0.69 | TSHR (0.33) | TSHRPDE4B | |
| SCHEMBL9856978 | 0.66 | KMT2A (0.41) | POLBALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159202-A | PHOTOCOPYING | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-26 | — | — | US | disclosed |