Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107990 | 0.84 | P2RX7 (0.57) | P2RX7TACR3 | |
| SCHEMBL22683927 | 0.72 | P2RX7 (0.56) | P2RX7TACR3 | |
| SCHEMBL31447391 | 0.69 | P2RX7 (0.52) | P2RX7TACR3 | |
| SCHEMBL1497560 | 0.66 | PDPK1 (0.50) | — | |
| SCHEMBL13209040 | 0.66 | POLB (0.49) | P2RX7 | |
| SCHEMBL1017946 | 0.64 | P2RX7 (0.54) | P2RX7TACR3 | |
| SCHEMBL16904 | 0.64 | ALDH1A1 (0.42) | — | |
| SCHEMBL28468317 | 0.64 | ALDH1A1 (0.42) | — | |
| SCHEMBL145307 | 0.64 | — | — | |
| SCHEMBL9079929 | 0.64 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475661-A1 | SULFONAMIDES AS INHIBITORS OF BCL-2 FAMILY PROTEINS FOR THE TREATMENT OF CANCER | Novartis AG (CH) | 2012-07-18 | — | — | EP | disclosed |
| WO-2011029842-A1 | SULFONAMIDES AS INHIBITORS OF BCL-2 FAMILY PROTEINS FOR THE TREATMENT OF CANCER | NOVARTIS AG (CH) | 2011-03-17 | — | — | WO | disclosed |
| WO-2011029842-A1 | SULFONAMIDES AS INHIBITORS OF BCL-2 FAMILY PROTEINS FOR THE TREATMENT OF CANCER | NOVARTIS AG (CH) | 2011-03-17 | — | — | WO | disclosed |