Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14973311 | 0.84 | TSHR (0.60) | MEP1BHDAC6TSHRNPSR1ALDH1A1 | |
| SCHEMBL4059272 | 0.83 | ALDH1A1 (0.63) | MEP1BHDAC2HDAC8HDAC6CYP2C19 | |
| SCHEMBL26731607 | 0.83 | CYP2C19 (0.70) | MEP1BCYP2C19TSHRNPSR1ALDH1A1 | |
| SCHEMBL2850679 | 0.82 | CYP2C19 (0.53) | MEP1BHDAC2HDAC8HDAC6CYP2C19 | |
| SCHEMBL26731616 | 0.81 | CYP2C19 (0.52) | MEP1BCYP2C19TSHRNPSR1ALDH1A1 | |
| SCHEMBL1348562 | 0.79 | ATM (0.62) | TSHRNPSR1ALDH1A1KMT2AATM | |
| Hydrochloric Acid SCHEMBL7966569 | 0.78 | ATM (0.61) | CYP2C19TSHRNPSR1ALDH1A1KMT2A | |
| SCHEMBL14972942 | 0.78 | LMNA (0.50) | MEP1BHDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL4237642 | 0.78 | ALDH1A1 (0.51) | MEP1BHDAC2HDAC8HDAC6CYP2C19 | |
| SCHEMBL4237644 | 0.78 | ALDH1A1 (0.51) | MEP1BHDAC2HDAC8HDAC6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604602-A1 | HETEROARYL-PYRAZOLE DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2013-06-19 | — | — | EP | disclosed |
| US-20130137865-A1 | HETEROARYL-PYRAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137865-A1 | HETEROARYL-PYRAZOLE DERIVATIVE | GRIN2C, GRIN2B, GRIN3A | MEP1B 3646/4885HDAC2 205/4885HDAC8 1570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.