Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14973616 | 0.85 | MAPT (0.44) | ALOX5ALDH1A1MAPK1NPSR1TSHR | |
| SCHEMBL14973686 | 0.84 | ALDH1A1 (0.39) | ALOX5ALDH1A1MAPK1NPSR1TSHR | |
| SCHEMBL14974205 | 0.77 | ALOX5 (0.43) | ALOX5ALDH1A1MAPK1NPSR1TSHR | |
| SCHEMBL14973881 | 0.76 | ALDH1A1 (0.48) | ALOX5ALDH1A1MAPK1NPSR1TSHR | |
| SCHEMBL14973944 | 0.75 | ALOX5 (0.44) | ALOX5ALDH1A1MAPK1NPSR1TSHR | |
| SCHEMBL14974066 | 0.75 | ALOX5 (0.45) | ALOX5ALDH1A1MAPK1NPSR1TSHR | |
| SCHEMBL14974200 | 0.72 | KMT2A (0.44) | ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL27867316 | 0.72 | ALOX5 (0.56) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14973615 | 0.72 | MAPT (0.45) | ALDH1A1MAPK1NPSR1TSHRMAPT | |
| SCHEMBL30440008 | 0.66 | ALDH1A1 (0.57) | ALDH1A1NPSR1TSHRMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | PEKING UNIVERSITY (CN) | 2013-05-30 | — | — | US | claimed |
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | PEKING UNIVERSITY (CN) | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | LTK, ERBB2, ABL1 | ALOX5 1076/4885ALDH1A1 2942/4885MAPK1 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.