Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14973687 | 0.84 | ALOX5 (0.40) | ALDH1A1TSHRMAPK1NPSR1SMN1; SMN2 | |
| SCHEMBL14973615 | 0.84 | MAPT (0.45) | ALDH1A1TSHRMAPK1NPSR1SMN1; SMN2 | |
| SCHEMBL14974204 | 0.76 | TP53 (0.43) | ALDH1A1TSHRMAPK1NPSR1SMN1; SMN2 | |
| SCHEMBL14973878 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TP53MAPT | |
| SCHEMBL14974065 | 0.74 | TSHR (0.44) | ALDH1A1TSHRMAPK1NPSR1POLB | |
| SCHEMBL14973943 | 0.73 | TP53 (0.43) | ALDH1A1TSHRMAPK1NPSR1POLB | |
| SCHEMBL14974198 | 0.71 | CHRNB2 (0.44) | ALDH1A1MAPK1NPSR1SMN1; SMN2MAPT | |
| SCHEMBL20982037 | 0.71 | POLB (0.40) | ALDH1A1NPSR1SMN1; SMN2POLBMAPT | |
| SCHEMBL14973616 | 0.70 | MAPT (0.44) | ALDH1A1TSHRMAPK1NPSR1POLB | |
| SCHEMBL27867316 | 0.68 | ALOX5 (0.56) | ALDH1A1SMN1; SMN2POLBTP53ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | PEKING UNIVERSITY (CN) | 2013-05-30 | — | — | US | claimed |
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | PEKING UNIVERSITY (CN) | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | LTK, ERBB2, ABL1 | ALDH1A1 2942/4885TSHR 521/4885MAPK1 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.