SCHEMBL1497428

SCHEMBL1497428

O=C(NC12CC3CC(C1)C(=S)C(C3)C2)OCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 6/20 0.51
FAAH O00519 4/20 0.50
CNR2 P34972 3/20 0.50
FKBP1A P62942 2/20 0.50
CNR1 P21554 1/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPK1 P28482 1/20 0.49
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
EPHX1 P07099 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1497415 0.89 EPHX2 (0.54) EPHX2FAAHCNR2FKBP1ACNR1
SCHEMBL1497397 0.83 FAAH (0.53) EPHX2FAAHCNR2FKBP1ACNR1
SCHEMBL13575195 0.81 EPHX2 (0.52) EPHX2FAAHCNR2FKBP1ACNR1
SCHEMBL13575194 0.81 EPHX2 (0.52) EPHX2FAAHCNR2FKBP1ACNR1
SCHEMBL1556682 0.81 EPHX2 (0.52) EPHX2FAAHCNR2FKBP1ACNR1
SCHEMBL17787705 0.81 EPHX2 (0.52) EPHX2FAAHCNR2FKBP1ACNR1
SCHEMBL16665110 0.81 EPHX2 (0.53) EPHX2FAAHCNR2FKBP1ACNR1
SCHEMBL10297219 0.81 EPHX2 (0.51) EPHX2FAAHCNR2FKBP1ACNR1
SCHEMBL974457 0.81 EPHX2 (0.51) EPHX2FAAHCNR2FKBP1ACNR1
SCHEMBL973910 0.81 EPHX2 (0.51) EPHX2FAAHCNR2FKBP1ACNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8440720-B2 Methods of use of antiviral compounds INFLUMEDIX, INC. (US) 2013-05-14 US disclosed
US-8440720-B2 Methods of use of antiviral compounds INFLUMEDIX, INC. (US) 2013-05-14 US disclosed
US-20110065766-A1 METHODS OF USE OF ANTIVIRAL COMPOUNDS INFLUMEDIX, INC. 2011-03-17 US disclosed
US-20110065766-A1 METHODS OF USE OF ANTIVIRAL COMPOUNDS INFLUMEDIX, INC. 2011-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110065766-A1 METHODS OF USE OF ANTIVIRAL COMPOUNDS MAVS, SLC30A5, HAVCR2 EPHX2 3743/4885FAAH 2661/4885CNR2 3873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.