Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 1.00 |
| ▸ | HTR1D | P28221 | 12/20 | 1.00 |
| ▸ | HTR1B | P28222 | 11/20 | 1.00 |
| ▸ | HTR2A | P28223 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920992 | 0.99 | HTR1A (0.97) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| SCHEMBL1913860 | 0.88 | HTR1A (0.81) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| Pyrrole SCHEMBL28770264 | 0.88 | HTR1A (0.85) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| SCHEMBL4512060 | 0.84 | HTR1A (1.00) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| SCHEMBL29018529 | 0.84 | HTR1A (0.78) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| SCHEMBL5461625 | 0.83 | HTR1A (0.71) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| Hydrochloric Acid SCHEMBL7809324 | 0.82 | HTR1A (0.97) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| SCHEMBL12809571 | 0.82 | HTR1A (0.70) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| SCHEMBL8299143 | 0.81 | HTR1A (0.77) | HTR1AHTR1DHTR1BHTR2AMAPT | |
| SCHEMBL10778563 | 0.81 | HTR1A (0.74) | HTR1AHTR1DHTR1BMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150024008-A1 | Methods and Compositions Involving Induced Senescent Cells for Cancer Treatment | UNIV CHICAGO (US) | 2015-01-22 | — | — | US | claimed |
| WO-2013078392-A1 | METHODS AND COMPOSITIONS INVOLVING INDUCED SENESCENT CELLS FOR CANCER TREATMENT | THE UNIVERSITY OF CHICAGO (US) | 2013-05-30 | — | — | WO | claimed |
| US-20240255509-A1 | COMPOSITIONS AND METHODS RELATED TO K180 DIMETHYLATED H1.0 PROTEIN | AELAN CELL TECH INC (US) | 2024-08-01 | — | — | US | disclosed |
| US-20230279147-A1 | H1.0K180ME2 ANTIBODIES, METHODS OF MAKING AND USES THEREOF | AELAN CELL TECH INC (US) | 2023-09-07 | — | — | US | disclosed |
| US-11505621-B2 | H1.0K180me2 antibodies, methods of making and uses thereof | AELAN CELL TECHNOLOGIES, INC. (US) | 2022-11-22 | — | — | US | disclosed |
| US-20200362056-A1 | H1.0K180ME2 ANTIBODIES, METHODS OF MAKING AND USES THEREOF | AELAN CELL TECHNOLOGIES, INC. (US) | 2020-11-19 | — | — | US | disclosed |
| CN-111770761-A | H1.0K180ME2 antibody, method for producing same, and use thereof | 爱兰细胞技术公司 | 2020-10-13 | — | — | CN | disclosed |
| EP-3700569-A1 | H1.0K180ME2 ANTIBODIES, METHODS OF MAKING AND USES THEREOF | Aelan Cell Technologies, Inc. (US) | 2020-09-02 | — | — | EP | disclosed |
| US-20190322729-A1 | COMPOSITIONS AND METHODS RELATED TO K180 DIMETHYLATED H1.0 PROTEIN | AELAN CELL TECHNOLOGIES, INC. | 2019-10-24 | — | — | US | disclosed |
| CN-109415431-A | COMPOSITIONS AND METHODS RELATED TO K180 DIMETHYLATED H1.0 PROTEIN | 爱兰细胞技术公司 | 2019-03-01 | — | — | CN | disclosed |
| WO-2017184895-A2 | COMPOSITIONS AND METHODS RELATED TO Κ180 DIMETHYLATED H1.0 PROTEIN | AELAN CELL TECHNOLOGIES, INC. (US) | 2017-10-26 | — | — | WO | disclosed |
| WO-2017002120-A1 | SELECTIVE INHIBITORS OF SENESCENT CELLS AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-01-05 | — | — | WO | disclosed |
| US-20150024008-A1 | Methods and Compositions Involving Induced Senescent Cells for Cancer Treatment | UNIV CHICAGO (US) | 2015-01-22 | — | — | US | disclosed |
| WO-2013078477-A2 | SOLUBILIZATION OF CURCUMINOID COMPOUNDS AND PRODUCTS THEREOF | PAYNE ADAM J (US) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013078392-A1 | METHODS AND COMPOSITIONS INVOLVING INDUCED SENESCENT CELLS FOR CANCER TREATMENT | THE UNIVERSITY OF CHICAGO (US) | 2013-05-30 | — | — | WO | disclosed |