Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CPT2 | P23786 | 2/20 | 0.44 |
| ▸ | CPT1A | P50416 | 2/20 | 0.44 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14976836 | 0.89 | KMT2A (0.57) | RORCCYP2D6MEN1KMT2ACPT2 | |
| SCHEMBL14976617 | 0.89 | MGLL (0.47) | RORCMEN1KMT2ACPT2CPT1A | |
| SCHEMBL5466669 | 0.84 | LMNA (0.54) | RORCMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL14976553 | 0.80 | RORC (0.54) | RORCCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5467556 | 0.78 | LMNA (0.55) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL2002912 | 0.78 | CPT1A (0.63) | RORCCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14987871 | 0.77 | RORC (0.51) | RORCCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL27295451 | 0.76 | DRD3 (0.57) | RORCMEN1KMT2ANR1H3MAPT | |
| SCHEMBL2001124 | 0.74 | CPT1A (0.54) | RORCCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14977169 | 0.73 | TDP1 (0.50) | CYP2C19MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013076590-A1 | BENZOTHIAZINE COMPOUNDS AS H3 RECEPTOR LIGANDS | OXYGEN HEALTHCARE RESEARCH PVT. LTD (IN) | 2013-05-30 | — | — | WO | disclosed |